| Impact factor |
Articles |
| 27.36 |
Ohsawa I, Ishikawa M, Takahashi K, et al. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med. 2007;13:688–94. [PubMed] |
| 7.05 |
Nagata K, Nakashima-Kamimura N, Mikami T, Ohsawa I, Ohta S. Consumption of molecular hydrogen prevents the stress-induced impairments in hippocampus-dependent learning tasks during chronic physical restraint in mice. Neuropsychopharmacology. 2009;34:501–8. [PubMed] |
| 6.65 |
Nakao A, Kaczorowski DJ, Wang Y, et al. Amelioration of rat cardiac cold ischemia/reperfusion injury with inhaled hydrogen or carbon monoxide, or both. J Heart Lung Transplant. 2010;29:544–53. [PubMed] |
| 5.68 |
Buchholz BM, Kaczorowski DJ, Sugimoto R, et al. Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury. Am J Transplant. 2008;8:2015–24. [PubMed] |
| 4.48 |
Huang CS, Kawamura T, Lee S, et al. Hydrogen inhalation ameliorates ventilator-induced lung injury.Crit Care. 2010;14:R234. [PMC free article] [PubMed] |
| 4.08 |
Yasuhiro Terasaki, Ikuroh Ohsawa, Mika Terasaki, Mikiko Takahashi, Shinobu Kunugi, Kang Dedong, Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress |
| 3.83 |
Kawamura T, Huang CS, Tochigi N, et al. Inhaled hydrogen gas therapy for prevention of lung transplant-induced ischemia/reperfusion injury in rats. Transplantation. 2010;90:1344–51. [PubMed] |
| 3.73 |
Kamimura N, Nishimaki K, Ohsawa I, Ohta S. Molecular Hydrogen Improves Obesity and Diabetes by Inducing Hepatic FGF21 and Stimulating Energy Metabolism in db/db Mice. Obesity (Silver Spring) 2011 in press. [PubMed] |
| 3.58 |
Nakayama M, Nakano H, Hamada H, Itami N, Nakazawa R, Ito S. A novel bioactive haemodialysis system using dissolved dihydrogen (H2) produced by water electrolysis: a clinical trial. Nephrol. Dial. Transplant. 2010;25:3026–33. [PubMed] |
| 3.4 |
Oharazawa H, Igarashi T, Yokota T, et al. Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury. Invest Ophthalmol Vis Sci. 2010;51:487–92. [PubMed] |
| 3.36 |
Kinji Ohno, Mikako Ito, Masatoshi Ichihara, and Masafumi Ito, Molecular Hydrogen as an Emerging Therapeutic Medical Gas for Neurodegenerative and Other Diseases, |
| 3.36 |
Chen CH, Manaenko A, Zhan Y, Liu WW, Ostrowki RP, Tang J, Zhang JH. Hydrogen gas reduced acute hyperglycemia-enhanced hemorrhagic transformation in a focal ischemia rat model. Neuroscience.2010;169:402–14. [PMC free article] [PubMed] |
| 3.23 |
Fujita K, Seike T, Yutsudo N, et al. Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. PLoS One.2009;4:e7247. [PMC free article] [PubMed] |
| 3.05 |
Xie KL, Yu YH, Pei YP, et al. Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and HMGB1 release. Shock. 2010;34:90–7. [PubMed] |
| 3.05 |
Xie K, Yu Y, Zhang Z, et al. Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model. Shock. 2010;34:495–501. [PubMed] |
| 2.98 |
Huang CS, Kawamura T, Toyoda Y, Nakao A. Recent advances in hydrogen research as a therapeutic medical gas. Free Radic Res. 2010;44:971–82. [PubMed] |
| 2.98 |
Qian L, Cao F, Cui J, et al. Radioprotective effect of hydrogen in cultured cells and mice. Free Radic Res. 2010;44:275–82. [PubMed] |
| 2.84 |
Cai JM, Kang ZM, Liu K, et al. Neuroprotective effects of hydrogen saline in neonatal hypoxia-ischemia rat model. Brain Res. 2009;1256:129–37. [PubMed] |
| 2.84 |
Li J, Wang C, Zhang JH, Cai JM, Cao YP, Sun XJ. Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer's disease by reduction of oxidative stress. Brain Res.2010;1328:152–61. [PubMed] |
| 2.84 |
Ji X, Liu W, Xie K, et al. Beneficial effects of hydrogen gas in a rat model of traumatic brain injury via reducing oxidative stress. Brain Res. 2010;1354:196–205. [PubMed] |
| 2.77 |
Nakashima-Kamimura N, Mori T, Ohsawa I, Asoh S, Ohta S. Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice.Cancer Chemother Pharmacol. 2009;64:753–61. [PubMed] |
| 2.59 |
Chen C, Chen Q, Mao Y, et al. Hydrogen-rich saline protects against spinal cord injury in rats.Neurochem Res. 2010;35:1111–8. [PubMed] |
| 2.47 |
Kajiyama S, Hasegawa G, Asano M, et al. Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Nutr Res. 2008;28:137–43. [PubMed] |
| 2.31 |
Domoki F, Olah O, Zimmermann A, et al. Hydrogen is neuroprotective and preserves cerebrovascular reactivity in asphyxiated newborn pigs. Pediatr Res. 2010;68:387–92. [PubMed] |
| 2.3 |
Fukuda K, Asoh S, Ishikawa M, Yamamoto Y, Ohsawa I, Ohta S. Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress. Biochem Biophys Res Commun. 2007;361:670–4. [PubMed] |
| 2.3 |
Hayashida K, Sano M, Ohsawa I, et al. Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury. Biochem Biophys Res Commun. 2008;373:30–5. [PubMed] |
| 2.3 |
Ohsawa I, Nishimaki K, Yamagata K, Ishikawa M, Ohta S. Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice. Biochem Biophys Res Commun. 2008;377:1195–8.[PubMed] |
| 2.3 |
Sato Y, Kajiyama S, Amano A, et al. Hydrogen-rich pure water prevents superoxide formation in brain slices of vitamin C-depleted SMP30/GNL knockout mice. Biochem Biophys Res Commun. 2008;375:346–50. [PubMed] |
| 2.3 |
Chen H, Sun YP, Li Y, et al. Hydrogen-rich saline ameliorates the severity of l-arginine-induced acute pancreatitis in rats. Biochem Biophys Res Commun. 2010;393:308–13. [PubMed] |
| 2.3 |
Itoh T, Fujita Y, Ito M, et al. Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells. Biochem Biophys Res Commun. 2009;389:651–6. [PubMed] |
| 2.19 |
Nakao A, Toyoda Y, Sharma P, Evans M, Guthrie N. Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study. J Clin Biochem Nutr. 2010;46:140–9. [PMC free article] [PubMed] |
| 2.19 |
Gu Y, Huang CS, Inoue T, Yamashita T, Ishida T, Kang KM, Nakao A. Drinking Hydrogen Water Ameliorated Cognitive Impairment in Senescence-Accelerated Mice. Journal of Clinical Biochemistry and Nutrition. 2010;46:269–76. [PMC free article] [PubMed] |
| 2.17 |
Sun Q, Kang Z, Cai J, et al. Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats. Exp Biol Med (Maywood) 2009;234:1212–9. [PubMed] |
| 2.03 |
Fu Y, Ito M, Fujita Y, et al. Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease. Neurosci Lett. 2009;453:81–5. [PubMed] |
| 1.8 |
Qian LR, Cao F, Cui JG, et al. The Potential Cardioprotective Effects of Hydrogen in Irradiated Mice. J. Radiat. Res. (Tokyo) 2010;51:741–7. [PubMed] |
| |
Bouchra Ghariba, Stéphane Hannaa, Ould M.S. Abdallahia, Hubert Lepidib, Bernard Gardettec,Max De Reggia*, Anti-inflammatory properties of molecularhydrogen: investigation on parasite-induced liverinflammation, liverinflammation |
| |
Cai J, Kang Z, Liu WW, et al. Hydrogen therapy reduces apoptosis in neonatal hypoxia-ischemia rat model. Neurosci Lett. 2008;441:167–72. [PubMed] |
| |
Ki Mun Kang, Yoshiya Toyoda, Tomohiro Kawamura, Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors |
| |
Mikako Ito1†, Tohru Ibi2†, Ko Sahashi3, Masashi Ichihara4, Masafumi Ito5and Kinji Ohno, Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies |
| |
Hirohisa Ono, Yoji Nishijima, Naoto Adachi, Shigekuni Tachibana, Shiroh Chitoku, Shigeo Mukaihara, Improved brain MRI induces in the acute brain stem infarct sites treated with hydroxyl radical scavengers, Edaravone and hydrogen, as compared to Edaravone alone, Anon-controlled study |
| |
Brandon J Dixon, Jiping Tang, John H Zhang, The evolution of molecular hydrogen: a notewrothy potential therapy with clinical significance |
| |
Mikako Ito, Masaaki Hirayama, Kazuaki Yamai, Sae Goto, Masafumi Ito , Masatoshi Ichihara and Kinji Ohno, Drinking hydrogen water and intermittent hydrogen gas exposure, but not lactulose or continuous hydrogen gas exposure, prevent 6-hydorxydopamine-induced Parkinson’s disease in rats |
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